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The new technologies of genomics, proteomics, and molecular immunology have led to an impressive increase in our knowledge of all aspects of virology, providing insights that can guide new vaccine concepts. When developing a new vaccine, the choice of approach is made very much on a case-by-case basis, and for a given virus is driven by knowledge its pathogenesis, serotype diversity, antigenic variation, immune evasion mechanisms, latency and route of transmission.

High importance is given to what type of immunity arises as a result of natural infection and whether the pathogen can cause persistent and/or repeated infections in a single host. This article discusses the medical need for new human viral vaccines and focuses on the strategies available for their development and some of the challenges posed by the more difficult targets.

To develop a new viral vaccine, get it licensed, and bring it to market is a lengthy, complex, and very expensive task. It requires a detailed knowledge of all aspects of the virus, especially its structure, epidemiology, pathology, and immunobiology, and demands a close collaboration between fundamental scientists, regulatory authorities, and industrial scientists and engineers. Completely new vaccines against human viruses appear infrequently on the market and the cost and complexity of their development has escalated with time, mainly due to the increased regulatory pressures to have highly defined products and to ensure complete clinical safety and high efficacy. 

When developing a new vaccine, the choice of approach is made very much on a case-by-case basis, and for a given virus is driven by knowledge of its biology, structure, antigenic diversity, and pathogenesis. High importance should be given to what type of immunity arises as a result of natural infection and whether the pathogen can cause persistent and/or repeated infections in a single host. Experiments in animal models may also allow the dissection of the immune response to identify correlates of protection. The use of primates in particular can be useful if the disease produced is similar to that observed in humans. However, many viruses are highly host specific and may have evolved strategies to evade immune responses that may also be host specific. Care must therefore be taken as results in animal models may not be entirely reproducible in the natural host.

This template will primarily be useful to medical professionals. You can use this template when preparing a population vaccination plan by creating a detailed plan for each category. You can also use this template when reporting on vaccinations in your area and providing statistics.

Vaccine Strategic Roadmap is a professional and modern template that contains six stylish and fully editable slides. If necessary, you can change all elements of the slide in accordance with your corporate requirements. This template will be useful for doctors, medical professionals and public relations specialists. Vaccine Strategic Roadmap Template will complement your presentations seamlessly and will be a great addition to your collection of professional presentations.